Searchable abstracts of presentations at key conferences in endocrinology

ea0038p174 | Neoplasia, cancer and late effects | SFEBES2015

Promoter methylation signatures of BRCA2 and TP53 genes in the serum of some breast cancer patients attending radiotherapy clinic in Lagos, Nigeria

Samuel Titilola , James Babatunde , Adara-Ali Ahmed , Fayoda Yetunde , Habeeb Mym

The prevalence of new cases of cancer in developing countries even though less than the developed countries have greater mortality rate, due to lack of access to treatment and early detection of the disease. Epigenetic alterations in BRCA2 and TP53, such as DNA methylation, maybe an effective approach in diagnosis, prognosis and therapy in breast cancer. This study examines the DNA methylation signature of BRCA2 and TP53 in Nigerian breast cancer patients. In this study, thirt...